Perseus Mining (ASX: PRU) welcomed new Managing Director and CEO Craig Jones this week, following the retirement of longstanding leader Jeff Quartermaine. Mr Jones joined Perseus with more than 25 years of global experience, having worked across Australia, Papua New Guinea (PNG), Indonesia and Canada, including as Newcrest’s global COO, with responsibility for five operating assets spread across multiple jurisdictions. Covered by Mining Weekly. The first portal firing also took place at Yaouré Gold Mine’s underground operation, officially opening the gateway to its underground mine – Perseus is now powering ahead towards first ore in January 2026.

Many Peaks Minerals (ASX: MPK) reported strong gold intercepts from recent assay results at its Ferké Gold project in Côte d’Ivoire. The reverse circulation drilling delivered notable results from both in-fill and reconnaissance targets situated north and south of the Ouarigue prospect - including: 24m @ 1.33g/t gold from surface, 7m @ 3.16g/t gold from 77m depth, 8m @ 1.80g/t gold from 61m, 3m @ 4.55g/t gold from 114m & 7m @ 0.96g/t gold from 27m.

Shaw and Partners Senior Research Analyst Philip Pepe highlighted Hazer Group (ASX: HZR) on the Talk Money To Me podcast, citing its hydrogen and graphite technology, early revenues, and JV partnerships as signs of progress, with significant upside potential as projects scale. Meanwhile, Hazer partnered with Veolia to test its graphite in water treatment, adding to potential offtake markets alongside clean hydrogen. Covered by Fuel Cells Work & Mining.com.au. Finally, its collaboration with EnergyPathways on the MESH project was recognised by the UK Government as nationally significant, providing fast-track approval status and supporting integration of its hydrogen, ammonia and graphite technology.

Axel REE (ASX: AXL) delivered a maiden rare earth MRE of 233Mt @ 2143ppm at its Caladão Project in Brazil, including 22% high-value magnet rare earth oxides (MREO/TREO). This follows on from the recently announced 100Mt Gallium MRE, firmly establishing Caladão as a globally significant dual-commodity critical minerals project. The REE resource, prepared by SRK Brazil, was modelled using conservative metallurgical recoveries capped at 31%, below Axel’s preliminary ANSTO testwork results of up to 52%, highlighting clear potential for a substantial resource upgrade. Covered by Stockhead and Proactive.

Victory Metals (ASX: VTM) strengthened its partnership with Japan’s Sumitomo Corporation, signing a non-binding Letter of Intent (LOI) to advance offtake and strategic cooperation for its North Stanmore REE Project in WA. The LOI sets out the offtake framework for North Stanmore’s Mixed Rare Earth Product (MREC), with Victory to supply up to 30% of annual production or 1,000 tonnes per year of MREC for an initial five-year period. Covered by Business News, Stockhead, Australian Mining and Mining.com.au.

Syntara (ASX: SNT) reported positive top-line Phase 2a data confirming the competitive profile of its lead candidate, amsulostat, in myelofibrosis. In combination with ruxolitinib, amsulostat delivered sustained clinical benefit out to 52 weeks, with 73% of patients achieving a ≥50% reduction in symptoms (TSS50) and 44% achieving spleen volume reduction (SVR25). Two patients recorded complete symptom resolution at 52 weeks, and several showed improvements in anaemia. The treatment was safe and well tolerated with no treatment-related serious adverse events. The results support progression to the next stage of clinical development and partnership engagement. Covered by Stockhead.

Chimeric Therapeutics (ASX: CHM) reported additional complete responses in its CORE-NK Phase 1b ADVENT-AML trial, with 57% of evaluable high-risk frontline AML patients showing clinical responses, including two new complete responses. Data presented at the Society of Hematology Oncology Annual Meeting confirmed the combination of CORE-NK cells with azacitidine and venetoclax is safe and well-tolerated, with no dose-limiting toxicities or unexpected safety issues. The results validate CORE-NK’s potential to enhance standard AML therapy, with the trial now advancing to dose expansion in newly diagnosed patients not eligible for intensive chemotherapy or transplant.

Ord Minnett released updated research on Lotus Resources (ASX: LOT) with a $0.35/share target. Senior Research Analyst Matthew Hope highlights that LOT is the firm's top pick in the ASX uranium space with 60% upside, highlighting a 'rich vein of catalysts' across the next six months. "Lotus is approaching commercial production at the Kayelekera mine and should now gain greater investor attention, with the spot uranium price rallying and peers looking pricey," he wrote. "The company has remained largely overlooked but is now entering production on a derisked mine with past production.”

METALS, MINING AND ENERGY

Aurum Resources (ASX: AUE) reported exceptional high-grade results from infill drilling at its 2.41Moz Boundiali Gold Project in Côte d’Ivoire, including 1m at 152.35 g/t gold from 96m. Additional intercepts at the BMT3 and BDT2 deposits returned grades such as 21m at 4.06 g/t Au and 5m at 10.80 g/t Au, confirming the continuity of high-grade mineralisation. With mineralisation open along strike and at depth, Aurum is advancing its 100,000m drilling program, major resource updates in early 2026, and a Pre-Feasibility Study at Boundiali, supported by a strong $40M cash position. Covered by Proactive & Business News.

Zeotech (ASX: ZEO) received firm commitments to raise $13 million to advance strategic initiatives through 2026, including mining operations at its Toondoon Kaolin Project, following a recent $200m binding offtake agreement with Jiangsu Mineral Sources International Trading Co; progressing a definitive feasibility study for its AusPozz™ Project for Australia’s first commercial production of high-reactivity metakaolin, and an expanded Toondoon drilling program to target an increase in the high-grade kaolin resource and produce a maiden Ore Reserve.

Lotus Resources (ASX: LOT) commenced resource infill drilling at its Letlhakane uranium project to support a Pre-Feasibility Study for the project. Drilling aims to upgrade its current Mineral Resource Estimate and provide metallurgical test samples to support a PFS, due in the second half of CY26. Letlhakane complements Lotus’ Kayelekera Mine in Malawi, which recently commenced uranium production.

Native Mineral Resources (ASX: NMR) generated cash receipts of $3,003,834 in the month of September as gold production at Blackjack, Qld continues to advance. Since production commenced on 30 July 2025, NMR has received $4,009,249 in cash, with its latest pour producing 393oz gold doré. Its latest pour was sourced from blended mineralised waste material; NMR will now move to higher-grade Blackjack and Far Fanning feed. Covered by Australian Mining.

Power Minerals (ASX: PNN) confirmed the presence of a high-grade carbonatite hard rock intrusion at its Santa Anna REE Project in Brazil, validating the project’s potential as a major ex-China critical minerals source. Drilling continues to deliver grades up to 6.2% TREO, with mineralisation starting at surface and remaining open in all directions. Expansion drilling and upcoming drone-based geophysical surveys aim to fast-track a maiden JORC Mineral Resource Estimate. Covered by Stockhead.

Larvotto Resources (ASX: LRV) reported positive results from the Gradient-Array IP and Resistivity survey at the Kiarra Prospect, part of the Hillgrove Antimony-Gold Project in NSW. The survey identified a strong correlation between resistivity highs and historic antimony-gold workings, confirming priority new drill targets for follow-up. Drilling is planned to test these targets and to continue to expand geophysical surveys across additional high-potential areas at Hillgrove. Covered by Mining.com.au and SMH.

Desert Metals (ASX: DM1) reported final assays from diamond drilling at the King Kong prospect, part of the Adzope Gold Project in Côte d’Ivoire, where 15 of the 17 holes drilled intersected anomalous gold over a 1.2km strike, confirming the potential for a significant, high-grade gold system. Results include a 400m semi-continuous mineralised zone at the southern end of the corridor, anchored by earlier intercept 17m at 7.5g/t gold from 262m. Desert Metals is preparing regional exploration at Adzope, including sampling at the expansive “Beach” prospect and aircore drilling at Tengrela South, where high-grade results have already been returned.

Toubani Resources (ASX: TRE) announced first results from its current drilling programs at its Kobada Gold Project in southern Mali, which identified broad zones of mineralisation outside the current Mineral Resource Estimate in both diamond core and reverse RC drilling programs. The Kobada project hosts 2.2Moz in Mineral Resources, which occurs over a 4.5km strike length and is predominantly oxide and open pitable. In addition, TRE also collected geotechnical and hydrological data to support the final mine design, expected later this year. Covered by Mining.com.au.

Strategic Energy Resources (ASX: SER) commenced a 1,500m diamond drill program at its Isa North Project in northwest Queensland to test gravity and magnetic iron oxide copper-gold targets (IOCG).  The campaign is expected to last four weeks before assays are returned in November, supported by a $250,000 grant from the Queensland Government. Covered by Mining.com.au.

Auric Mining (ASX: AWJ) successfully acquired the Burbanks Gold Processing Facility, strategically located just 10km south of Coolgardie, WA and within trucking distance from Auric’s tenements. Burbanks delivers critical infrastructure, supported by existing approvals and permits, positioning Auric to fast-track its strategy of becoming a fully integrated and sustainable gold producer in the heart of the Goldfields. Covered by Mining.com.au & The Sydney Morning Herald.

Magmatic Resources (ASX: MAG) completed a maiden drilling program at its Weebo Gold Project in WA’s Eastern Goldfields, covering over 3,190 metres across advanced targets at the Scone Stone and Ockerburry. Samples have been dispatched for assay and results are expected in the coming weeks. Weebo is strategically positioned between five multi-million-ounce gold mines.

Connected Minerals (ASX: CML) completed Phase 2 drilling program at the Etango North-East Uranium Project in Namibia. The campaign comprised 23 holes for 3,134 metres at the Ondapanda Prospect, following the outstanding Phase 1 results where 14 of 15 holes delivered economic uranium grades. Results are expected in 3 weeks. Covered by Mining.com.au.

Argent Minerals (ASX: ARD) received regulatory approvals for a follow-up diamond drill hole to test high-grade extensions of the Kempfield Silver-Polymetallic Project in NSW. The drillhole, to commence in coming weeks, will be collared along strike from AKDD208, which returned outstanding results including 22m @ 247.24 g/t Ag Eq and 42.6m @ 102.02 g/t Ag Eq. Covered by Stockhead.

Evergreen Lithium (ASX: EG1) will focus on advancing development work at its Mt Monger Gold Project, located  ~70km southeast from Kalgoorlie, WA. A recent site review highlighted the project’s strong advantages, including established infrastructure with haul roads and utilities, close proximity to six operating gold mines and three mills (one just 5km away). In addition, key approvals and logistical requirements for the initial drilling program are nearing completion. Covered by The Market Bull & ShareCafe.

Koba Resources: (ASX: KOB) has discovered a new high-grade prospect during initial follow-up drilling at its Yarramba Uranium Project in South Australia. Drilling continues to intersect uranium grades >1,000ppm eU₃O₈ including 1.07m @ 693ppm eU₃O₈ from 88.4m at the new Delord Prospect, including 0.53m @ 1,045ppm eU₃O₈; and 1.52m @ 482ppm eU₃O₈ from 86.5m; including 0.52m @ 1,071ppm eU₃O₈.

Chariot Corporation (ASX:CC99) announced an update on its Resurgent lithium project, located in the McDermitt Caldera on the Nevada–Oregon border in the United States. Resurgent is positioned immediately adjacent to Lithium Americas’ flagship Thacker Pass project, which is the largest lithium development in the United States. Covered by Stockhead and Mining.com.au.

Perpetual Resources (ASX: PEC) announced that assay results from the maiden drilling program at its Igrejinha Project in Brazil had confirmed the presence of a highly fertile and unique LCT pegmatite system, with exceptional grades across multiple critical minerals and pathfinder elements. Covered in Stockhead.

Andean Silver (ASX: ASL) welcomed experienced North American-based mining specialist Jessie Liu-Ernsting as a Non-Executive Director. Jessie is a highly credentialled resources executive and engineer with 20 years of experience in the mining industry. She has held progressively senior strategic, financial and technical positions at G Mining Ventures Corp. (TSX: GMIN), Hudbay Minerals Inc (NYSE: HBM), Resource Capital Funds and two preeminent Canadian EPCM firms.

Bellavista Resources (ASX: BVR) announced that the initial round of bioleaching experiments of hyper-enriched black shale mineralisation at the Brumby Project has confirmed critical & strategic minerals are present in the post experiment leachates.

BIOTECH

Chimeric Therapeutics (ASX: CHM) reported further signs of disease control and tumour shrinkage in its Phase 1/2 trial of CHM CDH17, with the Safety Monitoring Committee confirming Dose Level 2 is safe for ongoing exploration. Early results show tumour reductions of 12–37% and stable disease in colorectal and neuroendocrine cancer patients, while one Dose Level 1 patient remains in stable disease more than 10 months after a single dose. No off-target effects have been observed, supporting the continued development of CHM CDH17 as a novel CAR-T therapy for gastrointestinal cancers. Covered by Stockhead & Biotech Dispatch. 

Arovella's (ASX: AVA) unique and patent protected CLDN18.2 CAR has been demonstrated to induce effective killing of pancreatic cancer cells when incorporated into T cells in a proof-of-concept in vitro study. It performed equivalently to the leading CLDN18.2 CAR, and the anti-tumour activity of the CAR is anticipated to be superior in vivo when incorporated into Arovella’s iNKT cell platform. Arovella is proceeding to incorporate its CLDN18.2 CAR into iNKT cells, which will be followed up with in vivo pancreatic and gastric cancer studies in mice.

Radiopharm Theranostics (ASX: RAD) received a positive recommendation from the Data Safety and Monitoring Committee (DSMC) to advance its clinical-stage radiotherapeutic asset, 177Lu-RAD202 (RAD202), to the next dose level of 75mCi in the Phase 1 ‘HEAT’ clinical trial in patients with Human Epidermal Growth Factor Receptor 2 (HER2)-positive advanced solid tumors. The second cohort of patients is expected to be enrolled by Q4 2025.

Paradigm Biopharmaceuticals (ASX: PAR) has dosed participants in the pivotal PARA_OA_012 Phase 3 trial of iPP, with all selected sites currently expected to be activated and recruiting by the end of October. Early data shows an improved screen-failure rate versus PARA_OA_002, reflecting FDA-guided refinements to eligibility criteria, and PAR remains on track for an interim analysis in mid-CY2026.

CORPORATE NEWS

CurveBeam (ASX: CVB) received firm commitments for a $6.5 million placement, which attracted investment from new and existing institutional investors. The new funds will be used for research and development plus sales and marketing of its HiRise™ product, supply chain costs and general working capital purposes including capital raising fees. 

Syntara (ASX: SNT) appointed leading global myelofibrosis experts to support the development of its lead asset, amsulostat. Strategic advisors include Dr Adam Craig, former CEO of CTI BioPharma, and Dr Kevin Lynch, formerly of Celgene and Antengene. A new Clinical Advisory Board has also been established, featuring Professor Claire Harrison (Guy’s and St Thomas’ NHS Foundation Trust), Dr Gaby Hobbs (Harvard/Mass General Hospital), and Professor John Mascarenhas (Mount Sinai). The appointments strengthen Syntara’s clinical and commercial strategy as it advances amsulostat into a planned Phase 2b study.

Tungsten Mining (ASX: TGN) raised $9.5m via a placement to advance its Mt Mulgine gold-tungsten strategy. Funds will support testwork, engineering, mine planning and development, reinforcing the project’s status as one of the largest tungsten deposits outside China. Covered by Mining News.

Brazilian Critical Minerals (ASX:BCM) has raised A$6.0M through a well-supported placement, with funds to complete the feasibility study, progress permitting and advance offtake discussions at the Ema Rare Earths Project in Brazil, moving the project closer to commercial readiness.

NH3 Clean Energy (ASX: NH3) will host a shareholder webinar on 8 October at 12pm AEDT, outlining the WAH2 Project’s development, engineering milestones, & Pilbara-to-Asia supply chains. Register here

Syntara (ASX:SNT) Positive final Phase 2a amsulostat data webinar presentation

CurveBeam (ASX: CVB) - September 2025 Investor Presentation

Axel REE (ASX: AXL) Chairman Paul Dickson spoke to Proactive Investors following the delivery of the maiden 233Mt Rare Earth Resources at its Caladão Project in Brazil.